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3D Structures of Kelch-like protein

Updated on 30-August-2020 {{#tree:id=OrganizedByTopic|openlevels=0|

• Kelch-like protein 2

• • 2xn4 – hKLHL2 Kelch domain - human
    

• Kelch-like protein 3

• • 4chb, 4ch9, 5nkp – hKLHL3 Kelch domain + serine/threonine protein kinas WNK4 peptide
    
  • 4hxi – hKLHL3 BTB-BACK domain (mutant) + cullin-3 N terminal
    

• Kelch-like protein 4

• • 2eqx – hKLHL4 BACK domain - NMR
    

• Kelch-like protein 5

• • 4asc – hKLHL5 Kelch domain
    

• Kelch-like protein 7

• • 3ii7 – hKLHL7 Kelch domain
    

• Kelch-like protein 10

• • 2woz – KLHL10 Kelch domain - rat
    

• Kelch-like protein 11

• • 3i3n – hKLHL11 BTB-BACK domain
    
  • 4ap2, 4apf – hKLHL11 BTB-BACK domain + cullin-3 N terminal
    

• Kelch-like protein 12

• • 2vpj – hKLHL12 Kelch domain
    
  • 6ttk, 6v7o – hKLHL12 Kelch domain + peptide
    

• Kelch-like protein 16 (gigaxonin)

• • 3hve – hKLHL16
    
  • 2ppi – hKLHL16 BTB domain
    

• Kelch-like protein 17 (actinfilin)

• • 6hrl – hKLHL17
    

• Kelch-like protein 19 (kelch-like ECH-associated protein 1; Keap1)); domains: BTB 48-140; kelch 320-812

• • 1u6d, 1zgk, 4ifj, 6rog – hKeap1 Kelch domain
    
  • 3zgd, 5wfl – hKeap1 Kelch domain (mutant)
    
  • 4cxi, 4cxj, 6w68, 6w69 – hKeap1 BTB domain (mutant)
    
  • 1x2j – mKeap1 Kelch domain
    

• Keap1 complex with peptide

• • 4ifl, 2flu, 3zgc – hKeap1 Kelch domain + NRF2 Neh2 peptide
    
  • 5wfv, 5wg1 – hKeap1 Kelch domain (mutant) + NRF2 peptide
    
  • 6fmp, 6fmq – hKeap1 Kelch domain + peptide
    
  • 5f72 – hKeap1 Kelch domain + antibody
    
  • 5x54 – hKeap1 Kelch domain + tetrapeptide
    
  • 5nlb – hKLHL1 BTB+ 3-BOX domains + CUL-3
    
  • 4xmb – hKLHL1 Kelch domain + NRF2 activator
    
  • 5cgj – mKLHL1 Kelch domain + NRF2 activator - mouse
    
  • 1x2r – mKeap1 Kelch domain + NRF2 Neh2 peptide
    
  • 2z32 – mKeap1 Kelch domain + prothymosin a peptide
    
  • 3ade, 3wdz – mKeap1 Kelch domain + sequestosome-1 peptide
    
  • 2dyh – mKeap1 Kelch domain + NRF2 residues 22-36
    
  • 3wn7 – mKeap1 Kelch domain + NRF2 residues 17-51
    

• Keap1 complex with small molecule

• • 3vng, 3vnh, 6ffm – hKeap1 Kelch domain + oxadiazole derivative
    
  • 4ifn, 6tym, 6typ, [[6v6z] – hKeap1 Kelch domain + quinoline derivative
    
  • 4l7b, 4l7c, 4l7d 4n1b, 6uf0 – hKeap1 Kelch domain (mutant) + quinoline derivative
    
  • 4in4, 4zy3, 5fnq, 5fnr, 5fns, 5fnt, 5fnu, 5fzj, 5fzn, 6hws, 6sp1, 6sp4 – hKeap1 Kelch domain + inhibitor
    
  • 4iqk, 4n1b, 5wiy, 5whl, 5who – hKeap1 Kelch domain (mutant) + inhibitor
    
  • 5dad, 5daf – hKeap1 BTB domain + activator
    
  • 5git – hKeap1 BTB domain + inhibitor
    
  • 4cxt – hKeap1 BTB domain (mutant) + antagonist
    
  • 6qmc, 6qmd, 6qme, 6qmj, 6qmk – mKeap1 Kelch domain + inhibitor
    

• Keap1 complex with protein

• • 6w66 – hKeap1 BTB domain (mutant) + SKP1 + FBXL17
    
  • 6wcq – hKeap1 BTB domain (mutant) + SKP1 + FBXL17 + cullin-1 – Cryo EM
    

• Kelch-like protein 20

• • 5yq4 – hKLHL20 kelch domain
    
  • 6gy5 – hKLHL20 kelch domain + DAPK1 peptide
    

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