1qmc
From Proteopedia
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C-TERMINAL DNA-BINDING DOMAIN OF HIV-1 INTEGRASE, NMR, 42 STRUCTURES
Overview
The structure of the C-terminal DNA-binding domain of human immunovirus-1, integrase has been refined using nuclear magnetic resonance spectroscopy., The protein is a dimer in solution and shows a well-defined dimer, interface. The folding topology of the monomer consists of a five-stranded, beta-barrel that resembles that of Src homology 3 domains. Compared with, our previously reported structure, the structure is now defined far, better. The final 42 structures display a back-bone root mean square, deviation versus the average of 0.46 A. Correlation of the structure with, recent mutagenesis studies suggests two possible models for DNA binding., Proteins 1999;36:556-564.
About this Structure
1QMC is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
Refined solution structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase., Eijkelenboom AP, Sprangers R, Hard K, Puras Lutzke RA, Plasterk RH, Boelens R, Kaptein R, Proteins. 1999 Sep 1;36(4):556-64. PMID:10450096
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