Structural highlights
Publication Abstract from PubMed
Here we report that incorporation of an abasic site to DNA minidumbbells formed by natural sequences can lead to significant enhancements in their thermodynamic stability. Based on these stable minidumbbells, the first metal ion-controlled molecular switch which can regulate instant and reversible DNA duplex formation and dissociation has been constructed.
Rational design of a reversible Mg(2+)/EDTA-controlled molecular switch based on a DNA minidumbbell.,Wan L, Lam SL, Lee HK, Guo P Chem Commun (Camb). 2020 Sep 1;56(70):10127-10130. doi: 10.1039/d0cc03774e. PMID:32870195[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Wan L, Lam SL, Lee HK, Guo P. Rational design of a reversible Mg(2+)/EDTA-controlled molecular switch based on a DNA minidumbbell. Chem Commun (Camb). 2020 Sep 1;56(70):10127-10130. doi: 10.1039/d0cc03774e. PMID:32870195 doi:http://dx.doi.org/10.1039/d0cc03774e