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Pertussis toxin

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Revision as of 08:17, 21 September 2020 by Michal Harel (Talk | contribs)
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Pertussis toxin (PDB entry 1prt)

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3D Structures of Pertussis toxin

1prt – BpPT - Bordetella pertussis
1pto – BpPT + galactose
1bcp – BpPT + ATP
6ro0 – BpPT 1,2,5 subunits + islet-activating protein S2 + islet-activating protein S3 + islet-activating protein S4

Pertactin

1dab - BpPer
2iou - Per extracellular domain + major tropism determinant - Bordetella bronchiseptica

References

  1. Carbonetti NH, Artamonova GV, Andreasen C, Bushar N. Pertussis toxin and adenylate cyclase toxin provide a one-two punch for establishment of Bordetella pertussis infection of the respiratory tract. Infect Immun. 2005 May;73(5):2698-703. PMID:15845471 doi:http://dx.doi.org/10.1128/IAI.73.5.2698-2703.2005
  2. Connelly CE, Sun Y, Carbonetti NH. Pertussis toxin exacerbates and prolongs airway inflammatory responses during Bordetella pertussis infection. Infect Immun. 2012 Dec;80(12):4317-32. doi: 10.1128/IAI.00808-12. Epub 2012 Oct, 1. PMID:23027529 doi:http://dx.doi.org/10.1128/IAI.00808-12

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jonathan Tringali

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