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Function
Titin is a key component in the assembly and function of vertebrate striated muscles. Titin provides connections at the level of individual micro-filaments and contributes to the fine balance of forces between the two halves of the sarcomere. In non-muscle cells, titin plays a role in chromosome condensation and chromosome segregation during mitosis.
On the cellular level, titin is typically located within the nucleus of the cell; however, it can also be located within the cytoplasm.
Disease
Relevance
Structural highlights
Secondary structure
Secondary structure
