Sandbox GGC4
From Proteopedia
Contents |
Apolipoprotein
Function
Apolipoproteins are proteins that coat lipoprotein surface that binds lipids such as cholesterol, low-density lipoprotein (LDL), or high-density lipoproteins (HDL) in lipid metabolism. They function in the transport of such lipids in their structure that acts as a ligand to cell receptors and lipid transport proteins. Amphipathic structural behavior are what allows the interaction between hydrophobic properties of water, such as in the blood stream and hydrophobic lipids.
Apolipoprotein A-I is a protein APOA1 gene in humans that is a component of HDL, used in the transport of cholesterol phospholipids in the body through the bloodstream
Disease
Relevance
Structural highlights
Apolipoprotein a-1 consists of unique pseudo continuous highlighted by kinks at Pro residues, spaced approximately every 22 residues.
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References
1. Voet, D., Voet, J. G., & Pratt, C. W. (2016). Fundamentals of Biochemistry (5th ed.). Hoboken, NJ: John Wiley & Sons. 2. APOA1 gene: MedlinePlus Genetics. (2020, August 18). Retrieved October 26, 2020, from https://medlineplus.gov/genetics/gene/apoa1/
