1xl5

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Image:1xl5.gif

1xl5, resolution 1.73Å

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HIV-1 Protease in complex with amidhyroxysulfone

About this Structure

1XL5 is a Single protein structure of sequence from Human immunodeficiency virus 1 with CL and 190 as ligands. Active as HIV-1 retropepsin, with EC number 3.4.23.16 Full crystallographic information is available from OCA.

Reference

An old target revisited: two new privileged skeletons and an unexpected binding mode for HIV-protease inhibitors., Specker E, Bottcher J, Lilie H, Heine A, Schoop A, Muller G, Griebenow N, Klebe G, Angew Chem Int Ed Engl. 2005 May 13;44(20):3140-4. PMID:15822136

Page seeded by OCA on Thu Nov 8 14:35:43 2007

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