Structural highlights
Function
[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]
Publication Abstract from PubMed
Neutron diffraction studies of hydrogen/deuterium-exchanged hen egg-white lysozyme were performed by a joint X-ray and neutron refinement to elucidate the hydrogen/deuterium exchange behavior. Large crystals for neutron work, consisting of molecules that were exchanged before crystallization, were obtained by repeatedly adding protein solution to the crystal batch using deuterated precipitant reagent. There are differences in hydrogen/deuterium exchange behavior compared with previous crystallographic or NMR studies, which could be due to intermolecular interactions in the crystal or to different lengths of exchange period.
Hydrogen/deuterium exchange behavior in tetragonal hen egg-white lysozyme crystals affected by solution state.,Kita A, Morimoto Y J Appl Crystallogr. 2020 May 29;53(Pt 3):837-840. doi: 10.1107/S1600576720005488., eCollection 2020 Jun 1. PMID:32684898[2]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021
- ↑ Kita A, Morimoto Y. Hydrogen/deuterium exchange behavior in tetragonal hen egg-white lysozyme crystals affected by solution state. J Appl Crystallogr. 2020 May 29;53(Pt 3):837-840. doi: 10.1107/S1600576720005488., eCollection 2020 Jun 1. PMID:32684898 doi:http://dx.doi.org/10.1107/S1600576720005488
