1dxz
From Proteopedia
M2 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 20 STRUCTURES
Overview
A synthetic peptide corresponding to the transmembrane segment M2 (residues 236-267) of the alpha-subunit of the nicotinic acetylcholine receptor from Torpedo californica has been studied by two dimensional 1H-NMR spectroscopy in a chloroform-methanol (1:1) mixture containing 0.1 M LiClO4. Reconstruction of the spatial structure of M2 from the NMR data resulted in an alpha-helix formed by residues 241-263. Distribution of the molecular hydrophobicity potential on the helix surface is very similar to that in five-helix bundles of proteins with a known three dimensional structure: two hydrophilic bands located on the opposite helix sides separated by strong hydrophobic zones.
About this Structure
1DXZ is a Single protein structure of sequence from Torpedo californica. Full crystallographic information is available from OCA.
Reference
Spatial structure of the M2 transmembrane segment of the nicotinic acetylcholine receptor alpha-subunit., Pashkov VS, Maslennikov IV, Tchikin LD, Efremov RG, Ivanov VT, Arseniev AS, FEBS Lett. 1999 Aug 20;457(1):117-21. PMID:10486576 Page seeded by OCA on Fri May 2 14:25:00 2008
