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You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Function
- Moving cargo usually from the center of the cell to the periphery.
- Involved in cell replication.
Disease
- Charcot Marie Tooth (CMT)
Relevance
Structural highlights
- Scene #1
- Kinesin structure is composed of eight anti-parallel B sheets surrounded by three alpha helices on either side
- Scene #2
- This is the ATP binding site. Upon the binding of phosphate to ADP, ATP is formed giving Kinesin the energy needed to move the cargo one step a head to its destination
- Scene #3
- This is the Microtubule-binding site, where Kinesin binds to microtubules for stability
- Scene #4
- Charcot Marie Tooth is one of many diseases that affect the peripheral nervous system. Individuals may suffer physical disabilities due to weakness in transmission of signals firing from the central nervous system
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
