From Proteopedia
proteopedia linkproteopedia link Chordin
| This is a default text for your page Luke Houston/sandbox 1. Click above on edit this page to modify. Be careful with the < and > signs.
You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Where It is Found
Chordin is a protein that can be found within the embryos of different organisms. Although it can be seen with embryos, it is not seen within all embryos of every organism. The biological embryos that it can be seen are in the genus of the Xenopus. This is the scientific name of the organism. A name that more common folk would probably know would be African Clawed Frog. This particular frog can be found in Africa. More specifically, it is found sub-Sahara regions. The genus Xenopus genus includes the African Clawed Frog and roughly twenty other different aquatic organisms. Each of these various species possesses the chordin protein in their embryo structure. Another organism that this protein was discovered in is known as Drosophila. These are a genus of flies that are a part of the evolutionary family known as the Drosophilidae. More commonly known as either the fruit fly or a vinegar fly. These species of flies were also linked to the protein chordin in the same way the Xenopus species were, within the embryo of the fruit fly. These flies can be found all over the world. A third organism that scientists and researchers discovered this protein was inside the species known as the Danio rerio. Another, less scientific, name would be zebrafish. This organism belongs to the family of minnows. Most commonly, and native, to South Asia. Once again, found within embryo development of the fish. These three organisms are where it can be seen as the most popular containing the protein chordin. The research on these various species, and the use of these organisms, will allow a deeper understanding of the protein and how it impacts the biology and development of various life forms.
Function
The protein chordin has many different functions that it serves inside of the embryos of various organisms.
Disease
Relevance
Chordin is a very relevant and considerable component for understanding and researching the ways that various embryos develop from the time that they are conceived to birth. It can also be considered relevant in what organisms do with the protein and how they can affect their lives after development.
Structural highlights
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
|
References
Anderson, R., Lawrence, A., Stottmann, R., Bachiller, D., & Klingensmith, J. (2002, November 01). Chordin and Noggin promote organizing centers of forebrain development in the mouse. Retrieved March 28, 2021, from https://dev.biologists.org/content/129/21/4975
B. (n.d.). Chordin. Retrieved March 28, 2021, from https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/chordin
E. (n.d.). The chordin page. Retrieved March 28, 2021, from https://www.hhmi.ucla.edu/derobertis/EDR_MS/chd_page/chordin.html
Edward M. DE ROBERTIS. (n.d.). Retrieved March 28, 2021, from https://www.biolchem.ucla.edu/people/edward-m-de-robertis/
Plouhinec, J., Zakin, L., Moriyama, Y., & Robertis, E. (2013, December 17). Chordin forms a Self-organizing morphogen gradient in the extracellular space between Ectoderm and mesoderm in The Xenopus Embryo. Retrieved March 28, 2021, from https://www.pnas.org/content/110/51/20372
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644