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Enzyme-linked receptor
From Proteopedia
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Receptor protein serine/threonine kinases
TGF-beta receptor
Activin receptor
3D structure of the kinase domain of Activin receptor1 (Acvr1) complex with inhibitor shows with the protein including a and a [1]. Water molecule is shown as red sphere.
Receptor-like serine/threonine protein kinase
Bone morphogenetic protein receptors
Toll-like Receptors
See also:
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References and Notes
- ↑ Mohedas AH, Wang Y, Sanvitale CE, Canning P, Choi S, Xing X, Bullock AN, Cuny GD, Yu PB. Structure-activity relationship of 3,5-diaryl-2-aminopyridine ALK2 inhibitors reveals unaltered binding affinity for fibrodysplasia ossificans progressiva causing mutants. J Med Chem. 2014 Oct 9;57(19):7900-15. doi: 10.1021/jm501177w. Epub 2014 Sep 4. PMID:25101911 doi:http://dx.doi.org/10.1021/jm501177w