1atk

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Image:1atk.gif

1atk, resolution 2.20Å

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CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH THE COVALENT INHIBITOR E-64

Disease

Known disease associated with this structure: Pycnodysostosis OMIM:[601105]

About this Structure

1ATK is a Single protein structure of sequence from Homo sapiens with E64 as ligand. Active as Cathepsin K, with EC number 3.4.22.38 Full crystallographic information is available from OCA.

Reference

Crystal structure of human osteoclast cathepsin K complex with E-64., Zhao B, Janson CA, Amegadzie BY, D'Alessio K, Griffin C, Hanning CR, Jones C, Kurdyla J, McQueney M, Qiu X, Smith WW, Abdel-Meguid SS, Nat Struct Biol. 1997 Feb;4(2):109-11. PMID:9033588

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