Structural highlights
Function
[FKBP3_HUMAN] FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
Publication Abstract from PubMed
Human FKBP25, a nuclear protein, is a member of FK506 binding protein family (FKBP) and binds to immunosuppressive drugs such as FK506 and rapamycin. Human FKBP25 interacts with several nuclear proteins and regulates nuclear events. To understand the molecular basis of such interactions, we have performed NMR studies. Here, we report (1)H, (15)N and (13)C resonance assignments of the full-length human FKBP25 protein.
(1)H, (13)C and (15)N resonance assignments of human FK506 binding protein 25.,Prakash A, Shin J, Yoon HS Biomol NMR Assign. 2015 Apr;9(1):43-6. doi: 10.1007/s12104-014-9541-7. Epub 2014 , Jan 12. PMID:24414276[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Prakash A, Shin J, Yoon HS. (1)H, (13)C and (15)N resonance assignments of human FK506 binding protein 25. Biomol NMR Assign. 2015 Apr;9(1):43-6. doi: 10.1007/s12104-014-9541-7. Epub 2014 , Jan 12. PMID:24414276 doi:http://dx.doi.org/10.1007/s12104-014-9541-7
