Structural highlights
Publication Abstract from PubMed
Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.
Crystal structures of B-form DNA-RNA chimers complexed with distamycin.,Chen X, Ramakrishnan B, Sundaralingam M Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:7552741[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Chen X, Ramakrishnan B, Sundaralingam M. Crystal structures of B-form DNA-RNA chimers complexed with distamycin. Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:7552741