1ftn

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Template:STRUCTURE 1ftn

CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX


Overview

RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.

About this Structure

1FTN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995 Page seeded by OCA on Fri May 2 16:45:09 2008

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