ConSurf/Index
From Proteopedia
Here are listed pages in Proteopedia about evolutionary conservation, how to use the ConSurf Server, and how to interpret its results to identify functional sites in proteins.
Principles
- Introduction to Evolutionary Conservation: an explanation starting at the beginning, with examples.
- Conservation, Evolutionary covers
- How to locate conserved and variable patches
- Conservation expected to support folding of domains
- Unrelated sequences in the MSA obscure functional sites, re: ConSurfDB
- Comparing sequence-different chains
- Drift in results over time due to database growth
- Other evolutionary conservation servers besides ConSurf
Practical
- How to see conserved regions lists options and how to get started.
- ConSurf Quick Analysis Procedure: step by step for submitting a job to ConSurf.