Function
Shikimate kinase (SK) catalyzes the ATP-dependent phosphorylation of shikimate to produce shikimate 3-phosphate. It is part of the plant and bacteria pathway of synthesizing aromatic acids[1].
Relevance
SK inhibitors can be used as antimicrobial drugs[2].
Structural highlights
The active site of SK contains the substrate shikimate and an ADP molecule[3].
- . Water molecules are shown as red spheres.
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3D Structures of shikimate kinase
Shikimate kinase 3D structures
Updated on 21-March-2022
References