Ceramidase

From Proteopedia

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spinqualitylabelsall models PDB ID 2zxc Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image This is a default text for your page Pseudomonas aeruginosa neutral ceramidase CerN. Click above on edit this page to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue. Your Heading Here (maybe something like 'Structure') spinqualitylabelsall models Escherichia coli reca protein-bound DNA (PDB entry 3rec) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Anything in this section will appear adjacent to the 3D structure and will be scrollable.

Contents 1 Function 2 Disease 3 Relevance 4 Structural highlights 5 References

Function

CerN is a secreted enzyme that hydrolyzes the sphingolipid ceramide at the N-acyl linkage between the fatty acid and sphingosine base. ==Your Heading Here (maybe something like 'Structure')==

spinqualitylabelsall models Escherichia coli reca protein-bound DNA (PDB entry 3rec) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Disease

Relevance

Structural highlights

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

2zxc is a 2 chain structure with sequence from "bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, , , ,
Activity:	Ceramidase, with EC number 3.5.1.23
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

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References

1. ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
2. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644