Structural highlights
3pya is a 1 chain structure with sequence from Arath. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , |
| Gene: | At4g02780, GA1, T5J8.9, TPSGA1 (ARATH) |
| Activity: | Ent-copalyl diphosphate synthase, with EC number 5.5.1.13 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[KSA_ARATH] Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate.[1] [2]
References
- ↑ Prisic S, Xu J, Coates RM, Peters RJ. Probing the role of the DXDD motif in Class II diterpene cyclases. Chembiochem. 2007 May 25;8(8):869-74. PMID:17457817 doi:10.1002/cbic.200700045
- ↑ Mann FM, Prisic S, Davenport EK, Determan MK, Coates RM, Peters RJ. A single residue switch for Mg(2+)-dependent inhibition characterizes plant class II diterpene cyclases from primary and secondary metabolism. J Biol Chem. 2010 Jul 2;285(27):20558-63. doi: 10.1074/jbc.M110.123307. Epub 2010, Apr 29. PMID:20430888 doi:10.1074/jbc.M110.123307
