Vacuolar protein sorting-associated protein 3D structures

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3D structures of vacuolar protein sorting-associated protein

Updated on 21-June-2022- For a general description of the protein see Vacuolar protein sorting-associated protein {{#tree:id=OrganizedByTopic|openlevels=0|

  • Vps4 domains: MIT 1-82; AAA ATPase 124-437
    • 5xmi – yVps4 + ATP – yeast - Cryo EM
    • 2rko – yVps4 AAA ATPase domain
    • 3eie – yVps4 AAA ATPase domain (mutant)
    • 3eih – yVps4 AAA ATPase domain (mutant) + ATPγS
    • 2qp9 – yVps4 83-437
    • 2qpa – yVps4 (mutant) 83-437 + ADP
    • 2v6x – yVps4 MIT domain + yVps2 C-terminal
    • 4niq, 5fvk – yVps4 MIT domain + yVfa1 MIM2 domain
    • 5fvl – yVps4 MIT domain + yVPS20
    • 3mhv – yVps4 + yVps Vta1
    • 6ap1 – yVps4 + yVps Vta1 + peptide
    • 6oo2, 6ndy – yVps4 + yVps Vta1 + peptide - Cryo EM
    • 5uie – yVps4 + yVps2 + yVps Vta1 – Cryo EM
    • 5xmk – yVps4 (mutant) + yVps Vta1 + ATP – Cryo EM
    • 6bmf – yVps4 AAA ATPase domain + yVps2P – Cryo EM
  • Vps4A
    • 1yxr – hVps4A MIT domain – human - NMR
    • 2jq9 – hVps4A MIT domain + CHMP1A peptide - NMR
    • 2k3w – yVps4A MIT domain + CHMP6 peptide - NMR
  • Vps4B or Skd1
    • 2jqh, 2cpt, 1wr0 – hVps4B MIT domain - NMR
    • 1xwi – hVps4B C-terminal
    • 4u7y – hVps4B MIT domain + IST1 peptide
    • 2jqk – hVps4B MIT domain + CHMP2B
    • 7l9x – hVps4B + inhibitor
    • 2zam – mVps4B - mouse
    • 2zao – mVps4B + ADP
    • 2zan – mVps4B + ATP
  • Vps4P
    • 6ap1 – yVps4P + Vta1 + peptide + ADP - Cryo EM
  • Vps5
    • 6h7w – CtVps5 in retromer – Chaetomium thermophilum - Cryo EM
  • Vps9
    • 1mn3 – yVps9 CUE domain 398-451
    • 1p3q – yVps9 CUE domain + ubiquitin
  • Vps9A
    • 4g01 – Vps9A + RABF2B – Arabidopsis thaliana
  • Vps13
    • 6cbc – CtVps13 N-terminal (mutant)
  • Vps15 or serine/threonine protein kinase Vps15
    • 3gre – yVps15 WD repeat domain
  • Vps17
  • Vps23
    • 2f6m – yVps23 C-terminal (mutant) + yVps28 N-terminal
    • 3r42 – yVps23 N-terminal (mutant) + yVps27 peptide
    • 2caz – yVps23 + yVps28 N-terminal + SRN2
    • 2f66 – yVps23 C-terminal + yVps28 N-terminal + SRN2
    • 2p22 – yVps23 + yVps28 N-terminal + SRN2 + peptide
    • 1uzx – yVps23 UEV domain 1-161 + ubiquitin
  • Vps24
    • 6zh3 – yVps24 - Cryo EM
  • Vps25
    • 3htu – hVps23 C-terminal WH2 domain + hVps20 first helix
  • Vps 26
  • Vps 26A
    • 7blo – hVps26A + hVps35 + nexin-3 + DMT1 peptide - Cryo EM
    • 4p2a – mVps26A + sorting nexin-3
    • 6vac – mVps26A + Vps29 + Vps35
    • 6md5 – Vps26A – zebrafish
    • 7blq – CtVps26 + Vps35 + nexin-3 +Kex2 – Chaetomium thermophilum – Cryo EM
    • 5f0l, 5f0m, 5f0p – Vps26A + Vps35 + SNX3
  • Vps26B
  • Vps26-like
    • 6h7w – CtVps26L + Vsp29 + Vsp35 - Cryo EM
  • Vps27
    • 2pjw – yVps27 C-terminal + protein
    • 6njg – yVps27 + polyubiquitin
  • Vps28
    • 6vme – hVps28 in ESCRT-I complex
    • 2g3q, 2j9v – yVps28 C-terminal
    • 2j9u – yVps28 + yVps36
  • Vps29
    • 7bln – hVps29 + hVps35 - Cryo EM
    • 5wyh – hVps29 + interaptin
    • 5osh, 5osi – hVps29 + hVps35 + interaptin
    • 5gtu – hVps29 + TBC1D5
    • 3psn, 3pso – mVps29
    • [[6vacb] – mVps29 + Vps35 – Cryo EM
    • 2r17 – yVps29 + yVps35
    • 5w8m – CtVps29
    • 6xs5, 6xs7, 6xs8, 6xs9, 6xsa – CtVps29 + peptide
    • 6h7w – CtVps29 + CtVps35 + CtVps26-like + CtVPS - Cryo EM
    • 7blp, 7blr – CtVps29 + CtVps35 - Cryo EM
    • 5xce, 5xch – EhVps29 – Entamoeba histolytica
    • 5xcj, 5xck – EhVps29 (mutant)
  • Vps30
    • 3vp7 – hVps30 C-terminal
  • Vps33
    • 5bv1 – CtVps33 + CtVps16
    • 5bv0 – CtVps33 + CtVps16
  • Vps33A
    • 4bx8 – hVps33A
    • 4bx9 – hVps33A + hVps16 C-terminal + SNARE domain
  • Vps34
    • 5dfz – yVps34 + yVps38 + yVps15 + yVps30 + nanobody
  • Vps35
    • 5f0k – hVps35 N-terminal
    • 5f0j – hVps35 + hVps26A + sorting nexin-3
    • 5f0l, 5f0m, 5f0p – hVps35 + hVps26A + sorting nexin-3 + DMT-1
    • 6vac – mVps35 + mVps26A + mVps29 - Cryo EM
  • Vps36
    • 5kc2 – yVps36 + yVps15
    • 2hth – hVps36 GLUE domain 1-138 + ubiquitin
    • 2zme, 3cuq – hVps36 + hVps25 + SNF8
  • Vps45
  • Vps46
    • 3ggz – yVps46 MIM motif 176-204 + IST1
  • Vps53
    • 3ns4 – yVps53 C-terminal
  • Vps54
    • 3n1b – yVps54 C-terminal
    • 3n1e – mVps54 C-terminal
  • Vps60
    • 2luh – yVps60 + yVps Vta1 - NMR
  • Vps64
    • 6a8w – yVps64 FHA domain
  • Vps72
    • 6gej, 6gen – yVps72 in nucleosome – Cryo EM
  • Vps72 homolog
    • 5chl – Vps72 + histone H2A.Z – Drosophila melanogaster
    • 5fug – hVps72 N-terminal + histone H2A.Z
  • Vps74
  • Vps75
    • 3c9b, 3c9d, 5agc – yVps75
    • 3dm7 – yVps75 (mutant)
    • 2zd7 – yVps75 + peptide
    • 3q68, 3q66 – yVps75 + histone acetyltransferase
    • 3q33 – yVps75 + histone acetyltransferase + histone H3 peptide
    • 6o22 – yVps75 + histone acetyltransferase + histone H3 peptide + histone H4 peptide + ASF1 - NMR
    • 3q35 – yVps75 + histone acetyltransferase + acetyl CoA
    • 5yps – Vps75 (mutant) – Pneumocystis carinii
  • Vps Vta1 or Lip5
    • 2lxl – hVps Vta1
    • 4txp – hVps Vta1 N-terminal
    • 2rkk – yVps Vta1 N-terminal
    • 2rkl – yVps Vta1 C-terminal
    • 5h7p – yVps Vta1 N-terminal + yVps46 D1-D2 domain - NMR
    • 4u7e – hVps Vta1 N-terminal + IST1
    • 2lxm – hVps Vta1 N-terminal + CHMP5
    • 4txq – hVps Vta1 N-terminal + CHMP1B
    • 4txr – hVps Vta1 N-terminal + CHMP1B + CHMP5

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Michal Harel

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