Function
Ribokinase (RK) catalyzes the first step of ribose metabolism by phosphorylating it at the O5' position [1]. ATP serves as the co-substrate of RK.
Structural highlights
Upon forming a ternary complex of RK, ribose and nucleotide the RK dimer changes its open form to a closed one. The ribose substrate is seen between a small β-sheel domain and the concave side of the central β sheet[2]. is lined with charged residues. The is surrounded by hydrophobic residues.
Ribokinase 3D structures
Ribokinase 3D structures
