3v9d

Publication Abstract from PubMed

The crystal structure of the tetradecanucleotide sequence d(CCCCGGTACCGGGG)(2) has been determined at 2.5 A resolution in the tetragonal space group P4(1). This sequence was designed with the expectation of a four-way junction. However, the sequence crystallized as an A-DNA duplex and represents more than one full turn of the A-helix. The crystallographic asymmetric unit consists of one tetradecanucleotide duplex. The structural parameters of the A-type DNA duplex structure and the crystal-packing arrangement are described. One Mn(2+) ion was identified with direct coordination to the N7 position of G(13) and a water molecule at the major-groove side of the C(2).G(13) base pair.

Structure of the tetradecanucleotide d(CCCCGGTACCGGGG)2 as an A-DNA duplex.,Mandal PK, Venkadesh S, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Apr 1;68(Pt 4):393-9. Epub, 2012 Mar 27. PMID:22505405^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.