7y9v

Structural highlights

Function

[PINI_ARATH] Acts as a component of the auxin efflux carrier. Seems to be involved in the basipetal auxin transport. Mediates the formation of auxin gradient which is required to ensure correct organogenesis. Coordinated polar localization of PIN1 is directly regulated by the vesicle trafficking process and apical-basal PIN1 polarity also depends on the phosphorylation of conserved serine residues by PID kinase. The ARF-GEF protein GNOM is required for the correct recycling of PIN1 between the plasma membrane and endosomal compartments.^{[1] [2] [3]}

References

1. ↑ Benkova E, Michniewicz M, Sauer M, Teichmann T, Seifertova D, Jurgens G, Friml J. Local, efflux-dependent auxin gradients as a common module for plant organ formation. Cell. 2003 Nov 26;115(5):591-602. PMID:14651850
2. ↑ Huang F, Zago MK, Abas L, van Marion A, Galvan-Ampudia CS, Offringa R. Phosphorylation of conserved PIN motifs directs Arabidopsis PIN1 polarity and auxin transport. Plant Cell. 2010 Apr;22(4):1129-42. doi: 10.1105/tpc.109.072678. Epub 2010 Apr, 20. PMID:20407025 doi:http://dx.doi.org/10.1105/tpc.109.072678
3. ↑ Ganguly A, Lee SH, Cho M, Lee OR, Yoo H, Cho HT. Differential auxin-transporting activities of PIN-FORMED proteins in Arabidopsis root hair cells. Plant Physiol. 2010 Jul;153(3):1046-61. doi: 10.1104/pp.110.156505. Epub 2010 May, 3. PMID:20439545 doi:http://dx.doi.org/10.1104/pp.110.156505