Structural highlights
Function
[A5U1Y4_MYCTA] APS kinase catalyzes the synthesis of activated sulfate.[ARBA:ARBA00002357] Catalyzes the synthesis of activated sulfate.[HAMAP-Rule:MF_00065] With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.[HAMAP-Rule:MF_00062]