7zgx

Structural highlights

Function

[SLPA_DEIRA] Major constituent of the S-layer. Plays an important role in the structural organization and integrity of the S-layer (PubMed:16946272, PubMed:26074883). Binds the carotenoid deinoxanthin, a strong protective antioxidant specific of this bacterium, and could be part of the first lane of defense against UV radiation, especially under desiccation (PubMed:26909071).^{[1] [2] [3]}

References

1. ↑ Rothfuss H, Lara JC, Schmid AK, Lidstrom ME. Involvement of the S-layer proteins Hpi and SlpA in the maintenance of cell envelope integrity in Deinococcus radiodurans R1. Microbiology (Reading). 2006 Sep;152(Pt 9):2779-2787. doi: 10.1099/mic.0.28971-0. PMID:16946272 doi:http://dx.doi.org/10.1099/mic.0.28971-0
2. ↑ Farci D, Bowler MW, Esposito F, McSweeney S, Tramontano E, Piano D. Purification and characterization of DR_2577 (SlpA) a major S-layer protein from Deinococcus radiodurans. Front Microbiol. 2015 Jun 3;6:414. doi: 10.3389/fmicb.2015.00414. eCollection, 2015. PMID:26074883 doi:http://dx.doi.org/10.3389/fmicb.2015.00414
3. ↑ Farci D, Slavov C, Tramontano E, Piano D. The S-layer Protein DR_2577 Binds Deinoxanthin and under Desiccation Conditions Protects against UV-Radiation in Deinococcus radiodurans. Front Microbiol. 2016 Feb 16;7:155. doi: 10.3389/fmicb.2016.00155. eCollection, 2016. PMID:26909071 doi:http://dx.doi.org/10.3389/fmicb.2016.00155