Structural highlights
Function
[LCTC_ACEWD] The lactate dehydrogenase-Etf complex catalyzes the oxidation of lactate to pyruvate. It uses flavin-based electron confurcation to drive endergonic lactate oxidation with NAD(+) as oxidant at the expense of simultaneous exergonic electron flow from reduced ferredoxin to NAD(+). The electron transfer flavoprotein (Etf) mediates the electron transfer between the different donors and acceptors.[1]
References
- ↑ Weghoff MC, Bertsch J, Muller V. A novel mode of lactate metabolism in strictly anaerobic bacteria. Environ Microbiol. 2015 Mar;17(3):670-7. doi: 10.1111/1462-2920.12493. Epub 2014 , May 21. PMID:24762045 doi:http://dx.doi.org/10.1111/1462-2920.12493
