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3D Structures of Angiotensin-Converting Enzyme

Updated on 11-September-2022 {{#tree:id=OrganizedByTopic|openlevels=0|

• Angiotensin Converting Enzyme

• • 1o8a – hANCE - human
    
  • 2iul, 2iux, 3nxq, 4c2n, 4c2o, 4c2q, 4c2r – hANCE (mutant)
    
  • 2c6f – hANCE N domain
    
  • 7wa3 – miANCE - mink
    
  • 7c8k – baANCE – bat - Cryo EM
    
  • 2x8y – DmANCE – Drosophila melanogaster
    
  • 6s1y – moANCE N domain - mosquito
    

• Angiotensin Converting Enzyme N domain or RBD (1-641) complex

• • 6zpq, 6zpt - hANCE 1 (mutant)
    
  • 2c6n, 1o86, 4c2p, 2ydm, 1uze, 1uzf, 6h5x - hANCE 1 + drug
    
  • 7z6z - hANCE 1 (mutant) + drug
    
  • 6en5, 6en6, 4bzr, 6tt4 - hANCE 1 + inhibitor
    
  • 7q24, 7q25, 7q26, 7q27, 7q29 - hANCE 1 + inhibitor
    
  • 4bzs, 6tt3 – hANCE 1 mutant) + inhibitor
    
  • 6f9r, 6f9t, 6f9u, 6f9v - hANCE 1 + chronic heart failure drug
    
  • 7e7e - hANCE 2 + antibody
    

• • 7v61 – hANCE 2 + Na-dependent neutral amino acid

transporter + 3E8 – Cryo EM

• • 4bxk, 4ca5, 4ca7, 4ca8, 2xy9, 2xyd – hANCE 1 + phosphinic inhibitor
    
  • 4ca6, 6tt1 - hANCE 1 (mutant) + phosphinic inhibitor
    
  • 4aph – hANCE 1 + angiotensin II
    
  • 4apj, 6qs1 – hANCE 1 + bradykinin-potentiating peptide B
    
  • 1r42, 1r4l – hANCE 2 + disordered segment of collectrin homology domain
    

• • 2xhm – DmANCE+K inhibitor
    
  • 2x8z, 2x90, 2x91, 2x92, 2x93, 2x94, 2x95, 2x96, 2x97, 1j36, 1j37, 1j38, 3zqz – DmANCE+anti-hypertensive drug
    
  • 4aa1 – DmANCE 1 + angiotensin II
    
  • 4aa2, 4asr – DmANCE 1 + bradykinin-potentiating peptide B
    
  • 4asq – DmANCE 1 + bradykinin peptide
    
  • 6s1z – moANCE 2 + drug
    

• Angiotensin Converting Enzyme N domain or RBD (1-641) complex with spike glycoprotein

• • 3kbh, 3d0g, 3d0h, 3d0i, 2ajf, 3sci, 3scj, 3sck, 3scl, 6cs2, 6acg, 6acj, 6ack, 6lzg, 6m0j, 6vw1, 7drv, 7ekc, 7eke, 7ekf, 7ekg, 7ekh, 7lo4, 7p19, 7p8i, 7sn0, 7u0n, 76u, 7whh, 7xaz – hANCE 2 +spike glycoprotein
    
  • 7dmu, 7efp, 7efr , 7nxc, 7rpv – hANCE 2 (mutant) + SARS-Cov-2 spike glycoprotein
    
  • 7a91, 7a92, 7a94, 7a95, [7a96]], 7a97, 7a98, 7bh9, 7ct5, 7ddo, 7ddp, 7df4, 7dqa, 7dx5, 7dx6, 7dx7, 7dx8, 7dx9, 7edj, 7fdg, 7fdh, 7fdi, 7fem, 7kj2, 7kj3, 7kj4, 7kmb, 7kms, 7kmz, 7knb, 7kne, 7knh, 7kni, 7l7f, 7mjm, 7mjn, 7p8j, 7r0z, 7r10, 7r11, 7r12, 7r1a, 7t9k, 7t9l, 7tew, 7tex, , 7tez, 7te0, 7v7z, 7v80, 7v81, 7v82, 7v83, 7v84, 7v85, 7v86, 7v89, 7v8a, 7v8b, [[7vx4]7vx5, 7vx9, 7vxa, 7vxb, 7vxc, 7vxd, 7vxf, 7vxk, 7vxm, 7w8s, 7w98, 7w99, 7w9b, 7w9c, 7w9i, 7wa1, 7wgb, 7wgc, 7wk4, 7wk5, 7wk6, 7wpa, 7wpb, 7wpc, 7wri, 7ws8, 7ws9, 7wsa, 7wvp, 7wvq, 7xb0, 7xb1, 7xch, 7xci, 7xo7, 7xo8, 7xo9, 7zdq, 7zf7, 8dlv, 8dv1, 8dv2 – hANCE 2 + SARS-Cov-2 spike glycoprotein – Cryo EM
    
  • 7l0n, 7tn0 – hANCE 2 + SARS-Cov-2 spike glycoprotein + antibody
    
  • 7dx4, 7xcp, 7ydi, 7yeg, 8df5 – hANCE 2 + SARS-Cov-2 spike glycoprotein + antibody - Cryo EM
    
  • 7dwx – hANCE 2 + Na-dependent neutral amino acid transporter + SARS-Cov-2 spike glycoprotein – Cryo EM
    
  • 7fc5, 7fc6, 7w6r, 7xby – ANCE + SARS-Cov-2 spike glycoprotein – horse
    
  • 7wsk – ANCE + SARS-Cov-2 spike glycoprotein – civet
    
  • 7c8d – cANCE + SARS-Cov-2 spike glycoprotein – cat - Cryo EM
    
  • 7e3j – ANCE + SARS-Cov-2 spike glycoprotein – dog
    
  • 7fdk, 7xo4, 7xo5, 7xo6, 7xoa, 7xob, 7xoc – ANCE + SARS-Cov-2 spike glycoprotein – mouse – Cryo EM
    
  • 7c8j – baANCE + SARS-Cov-2 spike glycoprotein
    

• Angiotensin Converting Enzyme C domain (642-1232)

• • 6zpu – hANCE 1 (mutant)
    
  • 3l3n – hANCE 1 (mutant) +LISW
    
  • 3bkk, 3bkl – hANCE 1 +ketone inhibitor
    
  • 2oc2 – hANCE 1 +phosphinic inhibitor
    
  • 7q28 – hANCE 1 (mutant) + inhibitor
    
  • 6h5w, 7z70 - hANCE 1 (mutant) + anti-hypertensive drug
    

• Angiotensin Converting Enzyme residues 30-1240

• • 7q4c – hANCE 1 30-1240 – Cryo EM
    
  • 7q3y, 7q49, 7q4d, 7q4e – hANCE 1 (mutant) 30-1240 – Cryo EM
    

• Angiotensin Converting Enzyme C domain (642-1232)

• • 6zpu – hANCE 1
    
  • 3l3n – hANCE+LISW
    
  • 3bkk, 3bkl – hANCE+ketone inhibitor
    
  • 2oc2, 4ca5, 4ca7, 4ca8 - hANCE+phosphinic inhibitor
    
  • 6h5w - hANCE (mutant) + anti-hypertensive drug
    

• Angiotensin Converting Enzyme residues 2-805 complex

• • 6m1d – hANCE 2 + Na-dependent neutral amino acid transporter – Cryo EM
    
  • 6m17, 6m18 – hANCE 2 + Na-dependent neutral amino acid transporter + spike glycoprotein – Cryo EM
    
  • 7id – hANCE 2 (mutant) + spike glycoprotein – Cryo EM
    

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