Structural highlights
Function
GP46_BPSP1 Acts as a host growth inhibitor by inhibiting DNA-binding of microbial histone-like protein HU, thereby preventing chromosome segregation and causing filamentous cell morphology and growth defects in the host.[1]
References
- ↑ Zhang P, Zhao X, Wang Y, Du K, Wang Z, Yu J, Chang G, Matthews S, Wang H, Liu B. Bacteriophage protein Gp46 is a cross-species inhibitor of nucleoid-associated HU proteins. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9). pii: 2116278119. doi:, 10.1073/pnas.2116278119. PMID:35193978 doi:http://dx.doi.org/10.1073/pnas.2116278119
