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Introduction
Structural Highlights of HIV-1 proteases
Structural Highlights of HIV-2 proteases
HIV-1 Proteases in Humans
HIV-1 is more transmissible than HIV-2 and is more likely to lead to AIDS in a patient. “HIV-1 protease (PR) is a virus-encoded proteolytic enzyme that is initially systemized as part of the GagPol polyprotein” (Huang et. al, 2013). HIV-1 protease belongs to Clan AA, family A2 of the aspartic proteases. Aspartic proteases are the smallest group of proteases found in humans (Huang et. al, 2013).
HIV-2 Proteases in Humans
The role of CD4+ T-cell
Protease Inhibitors for HIV-1 Treatment
Protease Inhibitors for HIV-2 Treatment
Evolution's Role
HIV Prevention
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