Structural highlights
Function
ALDEC_PROMM Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane.[1]
Publication Abstract from PubMed
Biocatalytic propane production: structure-based engineering of aldehyde-deformylating oxygenase improves specificity for short- and medium-chain-length aldehydes and enhances the propane generation in whole-cell biotransformations. This presents new opportunities for developing biocatalytic modules for the production of volatile "drop-in" biofuels.
Production of Propane and Other Short-Chain Alkanes by Structure-Based Engineering of Ligand Specificity in Aldehyde-Deformylating Oxygenase.,Khara B, Menon N, Levy C, Mansell D, Das D, Marsh EN, Leys D, Scrutton NS Chembiochem. 2013 Jun 11. doi: 10.1002/cbic.201300307. PMID:23757044[2]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB. Microbial biosynthesis of alkanes. Science. 2010 Jul 30;329(5991):559-62. doi: 10.1126/science.1187936. PMID:20671186 doi:10.1126/science.1187936
- ↑ Khara B, Menon N, Levy C, Mansell D, Das D, Marsh EN, Leys D, Scrutton NS. Production of Propane and Other Short-Chain Alkanes by Structure-Based Engineering of Ligand Specificity in Aldehyde-Deformylating Oxygenase. Chembiochem. 2013 Jun 11. doi: 10.1002/cbic.201300307. PMID:23757044 doi:10.1002/cbic.201300307
