7wnu

Structural highlights

Function

RNJ_MYCTU An RNase that has 5'-3' exonuclease and possible endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity). Has both beta-lactamase and RNase activity, but the physiological relevance of the beta-lactamase activity, i.e. whether it confers antibiotic resistance, has not been shown (PubMed:21568871).^[1]

References

1. ↑ Sun L, Zhang L, Zhang H, He ZG. Characterization of a bifunctional beta-lactamase/ribonuclease and its interaction with a chaperone-like protein in the pathogen Mycobacterium tuberculosis H37Rv. Biochemistry (Mosc). 2011 Mar;76(3):350-8. doi: 10.1134/s0006297911030096. PMID:21568871 doi:http://dx.doi.org/10.1134/s0006297911030096