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3D Structures of Dynein

Updated on 08-February-2023 {{#tree:id=OrganizedByTopic|openlevels=0|

• Dynein light chain

• • 2e8j, 2b95, 1z09 - hDYNC 2A – human – NMR
    
  • 2hz5 - hDYNC 2A
    
  • 1y4o - mDYNC 2A – mouse
    
  • 1re6 - mDYNC 2 – NMR
    
  • 1pwj, 1pwk, 1f3c - rDYNC 2 – rat – NMR
    
  • 3dvt, 3bri - DmDYNC - Drosophila melanogaster
    
  • 3dvh - DmDYNC (mutant)
    
  • 1rhw - DmDYNC - NMR
    
  • 1ygt - DmDYNC TcTex1
    
  • 5hxl – rbfDYNC – rice blast fungus
    
  • 5wi4 - yDYNC TcTex1 - yeast
    
  • 5wof – DYNC 1 – Plasmodium falciparum
    
  • 1xdx, 1m9l, 1ds9 - CrDYNC TcTex1 – Chlamydomonas reinhardtii – NMR
    
  • 5yxm - CrDYNC
    
  • 3rjs - DYNC – Toxoplasma gondii
    

• Dynein light chain complex

• • 3zke, 3zkf, 6gzl, 6gzj, 7d35 - hDYNC 1 + peptide
    
  • 2xqq, 4d07, 7cnu - hDYNC 2 + peptide
    
  • 3p8m - hDYNC 2 + GCN4
    
  • 3tq7 – hDYNC 1 + EB1C/EB3C
    
  • 1f95, 1f96 - rDYNC + peptide – NMR
    
  • 4qh8, 4qh7 - DmDYNC + anastral spindle 2
    
  • 3dvp, 3brl, 3e2b, 5e0l, 5e0m, 7k3j, 7k3k, 7k3l - DmDYNC + peptide
    
  • 4ds1 - yDYNC + nucleoporin Nup129 peptide
    
  • 4ht6 – yDYNC + PAC11 peptide
    
  • 6l4p – CrDYNC + DYNC heavy chain 1614-1757
    
  • 7jts – CrDYNC + radial spoke protein + microtubules + calmodulin – Cryo EM
    
  • 7jtk – CrDYNC + radial spoke protein + cytochrome b5 heme-binding domain containing protein – Cryo EM
    

• Dynein intermediate chain

• • 3l7h – DmDYNC intermediate chain light chain roadblock
    
  • 3l9k - DmDYNC intermediate chain light chain roadblock + intermediate chain
    
  • 3fm7, 3glw, 2pg1, 2p2t - DmDYNC intermediate chain + light chain
    
  • 5hyc – rbfDYNC 2
    
  • 6pqt – CtDYNC N-terminal – Chaetomium thermophilum - NMR
    

• Dynein light+intermediate chains

• • 5jpw – hDYNC - NMR
    
  • 6f1z – hDYNC – Cryo EM
    
  • 6b9h - hDYNC + protein hook homolog
    
  • 6rlb, 6sc2 – hDYNC + alkylguanine-DNA alkyltransferase + WD repeat-containing proteins 60+34 – Cryo EM
    
  • 4w7g – CtDYNC
    

• Dynein heavy chain

• • 5nug, 6f1v – hDYNC – Cryo EM
    
  • 5owo – hDYNC
    
  • 8dyu, 8dyv – hDYNC + PAFAH – Cryo EM
    
  • 5ayh – mDYNC
    
  • 3err - mDYNC microtubule-binding domain/Ser-tRNA synthetase
    
  • 3wuq - mDYNC stalk domain
    
  • 3j1t - mDYNC + tubulin α-1B chain
    
  • 3j1u - mDYNC + tubulin α-1B+β-2B chains
    
  • 6rza, 6rzb - mDYNC microtubule-binding domain + tubulin α-1B+β-2B chains – Cryo EM<r />
  • 6kjn – yDYNC 3095-3232 - NMR
    
  • 6kjo – yDYNC 3095-3232 (mutant) - NMR
    
  • 5afr – yDYNC N terminal 1-557
    
  • 3qmz – yDYNC 1364-4092 + glutathione-S-transferase
    
  • 4w8f – yDYNC/lysozyme (mutant) + AMPPNP
    
  • 5vh9, 5vlj – yDYNC 1448-3028,3298-4092 + LIS1 + ATP - CryoEM
    
  • 6kio, 6kiq – yDYNC 3095-3224 + pTubulin α-1A+β chains – Cryo EM
    
  • 3vkg, 3vkh - DYNC – Dictyostelium discoideum
    
  • 2rr7 – CrDYNC microtubule-binding domain
    
  • 3j6p - DYNC + tubulin α-1B chain – slime mold
    
  • 6zyy – TtDYNC + shulin + ADP + ATP - Tetrahymena thermophila - Cryo EM
    

• Dynein motor domain

• • 4rh7 – hDYNC + ADP + ATP
    
  • 7z8f, 7z8g, 7z8h, 7z8i, 7z8j, 7z8k, 7z8l – hDYNC (mutant) + ADP + ATP + ANP – Cryo EM<br
  • 6rla – hDYNC/alkylguanine-DNA alkyltransferase + ADP + ATP – Cryo EM
    
  • 3j68, 3j67 – DYNC – sea urchin
    
  • 4aki, 4akg – yDYNC + ATP
    
  • 4akh – yDYNC + AMPPNP
    
  • 4ai6 – yDYNC + ADP
    
  • 7mi1 – yDYNC/endolysin
    
  • 7mi3, 7mi6, 7mi8 – yDYNC/endolysin + ATP + pyrimidine derivative – Cryo EM
    

• Dynein tail

• • 6f1y – hDYNC heavy+light+intermediate – CryoEM
    
  • 5nvs – hDYNC heavy+light+intermediate + LC8 + TcTex + ROBL – CryoEM
    
  • 5nvu – hDYNC motor+heavy+light+intermediate + LC8 + TcTex + ROBL – CryoEM
    
  • 5nw4 – hDYNC heavy+light+intermediate + APR1 + APR11 + ROBL + beta-actin + capping protein + dynactin + P150 + BICD2N – CryoEM
    
  • 5afu – pDYNC subunits 2,3,5,6 + dynein tail + capping protein - pig – CryoEM
    
  • 6f3a – pDYNC heavy+light+intermediate + dynactin + BICD2N - Cryo EM
    
  • 6f1u, 6f1t – pDYNC heavy+light+intermediate + dynactin + BICDR1 - Cryo EM
    
  • 6f38 – pDYNC heavy+light+intermediate + dynactin + HOOK3 - Cryo EM
    
  • 6zyx – TtDYNC heavy+light+intermediate + shulin + GTP - Cryo EM
    

• Dynein arm core subcomplex

• • 7k58, 7k5b, 7kek, 7kzn, 7kzo – CrDYNC + DC1 + DC2 – CryoEM
    
  • 7kzm – CrDYNC + DC1 + DC2 + DC3 + GDP + GTP – CryoEM
    
  • [[6zyw], 7moq – TtDYNC + thioredoxin + shulin + ADP + ATP + GTP – CryoEM
    

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