Thyroid Stimulating Hormone Receptor (TSHR) Structure and Function
Introduction
Insert background about TSHR here.
Structural Overview
Describe the domains here.
Activation
Hinge Motion
Describe the hinge motion and biological function here.
This shows the TSHR hinge movement.
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- Image:TSHR MorphBetterAngle.mp4
Stabilizing Interactions in the Hinge
Describe important structural features of the hinge here.
Ligand Binding
Ligand-induced Conformation Change
Describe how TSH binds in the upright conformation here.
Ligand Recognition
Describe seatbelt and hinge important to ligand recognition here.
References
