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1kqg
From Proteopedia
FORMATE DEHYDROGENASE N FROM E. COLI
Overview
The structure of the membrane protein formate dehydrogenase-N (Fdn-N), a major component of Escherichia coli nitrate respiration, has been determined at 1.6 angstroms. The structure demonstrates 11 redox centers, including molybdopterin-guanine dinucleotides, five [4Fe-4S] clusters, two heme b groups, and a menaquinone analog. These redox centers are aligned in a single chain, which extends almost 90 angstroms through the enzyme. The menaquinone reduction site associated with a possible proton pathway was also characterized. This structure provides critical insights into the proton motive force generation by redox loop, a common mechanism among a wide range of respiratory enzymes.
About this Structure
1KQG is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Molecular basis of proton motive force generation: structure of formate dehydrogenase-N., Jormakka M, Tornroth S, Byrne B, Iwata S, Science. 2002 Mar 8;295(5561):1863-8. PMID:11884747 Page seeded by OCA on Fri May 2 23:02:48 2008
Categories: Escherichia coli | Formate dehydrogenase | Protein complex | Byrne, B. | Iwata, S. | Jormakka, M. | Tornroth, S. | Anaerobic | Dehydrogenase | Fe4s4 | Formate | Integral membrane protein | Iron sulfur cluster | Mgd | Molybdenum | Molybdopterin | Molybdopterin guanine dinucleotide | Mpt | Oxidoreductase | Secy | Selenium | Selenocysteine
