Structural highlights
Function
TAF3_MOUSE Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Deato MD, Tjian R. Switching of the core transcription machinery during myogenesis. Genes Dev. 2007 Sep 1;21(17):2137-49. Epub 2007 Aug 17. PMID:17704303 doi:http://dx.doi.org/10.1101/gad.1583407
