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Pertussis toxin

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3D Structures of Pertussis toxin

- 1prt – BpPT - Bordetella pertussis
- 1pto – BpPT + galactose
- 1bcp – BpPT + ATP
- 6ro0 – BpPT 1,2,5 subunits + islet-activating protein S2 + islet-activating protein S3 + islet-activating protein S4
- 7ski – BpPT subunit 1 + phenanthridine derivative
- 7sky – BpPT subunit 1 + NAD
- 7u6z – BpPT subunit 1 (mutant) + NAD
- 7sne – BpPT subunit 1 + BaAD
- 7skk – BpPT subunit 1 + ADPR + nicotinamide

Pertussis-like toxin

- 4z9d – EcPLT subunit A (mutant) – Escherichia coli
- 4z9c – EcPLT subunits A,B
- 7k7h – SaPLT subunits A,B + antibody – Salmonella enterica – Cryo EM

Pertactin

- 1dab - BpPer
- 2iou - Per extracellular domain + major tropism determinant - Bordetella bronchiseptica

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References

↑ Carbonetti NH, Artamonova GV, Andreasen C, Bushar N. Pertussis toxin and adenylate cyclase toxin provide a one-two punch for establishment of Bordetella pertussis infection of the respiratory tract. Infect Immun. 2005 May;73(5):2698-703. PMID:15845471 doi:http://dx.doi.org/10.1128/IAI.73.5.2698-2703.2005
↑ Connelly CE, Sun Y, Carbonetti NH. Pertussis toxin exacerbates and prolongs airway inflammatory responses during Bordetella pertussis infection. Infect Immun. 2012 Dec;80(12):4317-32. doi: 10.1128/IAI.00808-12. Epub 2012 Oct, 1. PMID:23027529 doi:http://dx.doi.org/10.1128/IAI.00808-12