1mh1

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Image:1mh1.gif

1mh1, resolution 1.38Å

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SMALL G-PROTEIN

Overview

The crystal structure of human rac1, a member of the rho family of small, G-proteins, complexed with the non-hydrolysable GTP analogue, guanosine-5'-(beta gamma-imino)triphosphate (GMPPNP), has been determined, by X-ray analysis at a resolution of 1.38 A. Comparison with the structure, of H-ras indicates that rac1 has an extra alpha-helical domain that is, characteristic of the rho G proteins, and may be involved in the, signalling pathway of this family.

About this Structure

1MH1 is a Single protein structure of sequence from Homo sapiens with MG and GNP as ligands. Full crystallographic information is available from OCA.

Reference

The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue., Hirshberg M, Stockley RW, Dodson G, Webb MR, Nat Struct Biol. 1997 Feb;4(2):147-52. PMID:9033596

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