1n56

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Image:1n56.gif

Template:STRUCTURE 1n56

Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion


Overview

Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.

About this Structure

1N56 is a Single protein structure of sequence from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

Reference

Error-prone DNA polymerases: novel structures and the benefits of infidelity., Friedberg EC, Fischhaber PL, Kisker C, Cell. 2001 Oct 5;107(1):9-12. PMID:11595180 Page seeded by OCA on Sat May 3 02:06:34 2008

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