Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with Cytisine
5syo is a 5 chain structure with sequence from Aplysia californica and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
ACHA3_HUMAN After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.Q8WSF8_APLCA