Structural highlights
Function
KCTD5_HUMAN Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4.[1]
References
- ↑ Bayon Y, Trinidad AG, de la Puerta ML, Del Carmen Rodriguez M, Bogetz J, Rojas A, De Pereda JM, Rahmouni S, Williams S, Matsuzawa S, Reed JC, Crespo MS, Mustelin T, Alonso A. KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases. FEBS J. 2008 Aug;275(15):3900-10. doi: 10.1111/j.1742-4658.2008.06537.x. Epub, 2008 Jun 28. PMID:18573101 doi:http://dx.doi.org/10.1111/j.1742-4658.2008.06537.x
