1nci
From Proteopedia
STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS
Overview
Crystal structures of the amino-terminal domain of N-cadherin provide a picture at the atomic level of a specific adhesive contact between cells. A repeated set of dimer interfaces is common to the structure in three lattices. These interactions combine to form a linear zipper of molecules that mirrors the linear structure of the intracellular filaments with which cadherins associate. This cell-adhesion zipper may provide a mechanism to marshal individual molecular adhesive interactions into strong bonds between cells.
About this Structure
1NCI is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:7885471 Page seeded by OCA on Sat May 3 02:22:09 2008
