1nik

From Proteopedia

Revision as of 23:34, 2 May 2008 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 1nik

Wild Type RNA Polymerase II


Overview

The x-ray structure of complete RNA polymerase II from Saccharomyces cerevisiae has been determined, including a heterodimer of subunits Rpb4 and Rpb7 not present in previous "core" polymerase II structures. The heterodimer maintains the polymerase in the conformation of a transcribing complex, may bind RNA as it emerges from the enzyme, and is in a position to interact with general transcription factors and the Mediator of transcriptional regulation.

About this Structure

1NIK is a Protein complex structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription., Bushnell DA, Kornberg RD, Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):6969-73. Epub 2003 May 13. PMID:12746498 Page seeded by OCA on Sat May 3 02:34:39 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools