Structural highlights
5wro is a 1 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
|
| Method: | X-ray diffraction, Resolution 2.015Å |
| Ligands: | , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
ENO_DROME
Publication Abstract from PubMed
Enolase is an important enzyme in glycolysis and various biological processes. Its dysfunction is closely associated with diseases. Here, the enolase from Drosophila melanogaster (DmENO) was purified and crystallized. A crystal of DmENO diffracted to 2.0 A resolution and belonged to space group R32. The structure was solved by molecular replacement. Like most enolases, DmENO forms a homodimer with conserved residues in the dimer interface. DmENO possesses an open conformation in this structure and contains conserved elements for catalytic activity. This work provides a structural basis for further functional and evolutionary studies of enolase.
Crystal structure of enolase from Drosophila melanogaster.,Sun C, Xu B, Liu X, Zhang Z, Su Z Acta Crystallogr F Struct Biol Commun. 2017 Apr 1;73(Pt 4):228-234. doi:, 10.1107/S2053230X17004022. Epub 2017 Mar 22. PMID:28368282[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Sun C, Xu B, Liu X, Zhang Z, Su Z. Crystal structure of enolase from Drosophila melanogaster. Acta Crystallogr F Struct Biol Commun. 2017 Apr 1;73(Pt 4):228-234. doi:, 10.1107/S2053230X17004022. Epub 2017 Mar 22. PMID:28368282 doi:http://dx.doi.org/10.1107/S2053230X17004022
