Structural highlights
Function
TRIM3_HUMAN Probably involved in vesicular trafficking via its association with the CART complex (PubMed:15772161). The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Positively regulates motility of microtubule-dependent motor protein KIF21B (By similarity).[UniProtKB:Q9R1R2][1]
References
- ↑ Yan Q, Sun W, Kujala P, Lotfi Y, Vida TA, Bean AJ. CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling. Mol Biol Cell. 2005 May;16(5):2470-82. Epub 2005 Mar 16. PMID:15772161 doi:http://dx.doi.org/E04-11-1014
