Structural highlights
Function
ACES_ANOGA Rapidly hydrolyzes choline released into the synapse.
Publication Abstract from PubMed
Acetylcholinesterase (AChE) hydrolyzes the neurotransmitter acetylcholine at cholinergic synapses in the central nervous system (Toutant, 1989). Inhibition of the enzyme in insects could lead to the death of insects rapidly; thus AChE has been a molecular target for developing insecticides. This article is protected by copyright. All rights reserved.
Crystal structure of acetylcholinesterase catalytic subunits of the malaria vector Anopheles gambiae.,Han Q, Wong DM, Robinson H, Ding H, Lam PC, Totrov MM, Carlier PR, Li J Insect Sci. 2017 Mar 1. doi: 10.1111/1744-7917.12450. PMID:28247978[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Han Q, Wong DM, Robinson H, Ding H, Lam PC, Totrov MM, Carlier PR, Li J. Crystal structure of acetylcholinesterase catalytic subunits of the malaria vector Anopheles gambiae. Insect Sci. 2017 Mar 1. doi: 10.1111/1744-7917.12450. PMID:28247978 doi:http://dx.doi.org/10.1111/1744-7917.12450
