Structural highlights
Function
MYG_PHYMC Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
Publication Abstract from PubMed
A de novo designed intramolecular disulfide bond in myoglobin, resembling that in cytoglobin without structural evidence, was confirmed by an X-ray structure for the first time and was demonstrated to regulate both the structure and function of this protein, which fulfills the design of an artificial dehaloperoxidase, with an activity exceeding that of a native enzyme.
Regulation of both the structure and function by a de novo designed disulfide bond: a case study of heme proteins in myoglobin.,Yin LL, Yuan H, Du KJ, He B, Gao SQ, Wen GB, Tan X, Lin YW Chem Commun (Camb). 2018 Apr 24;54(34):4356-4359. doi: 10.1039/c8cc01646a. PMID:29645029[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Yin LL, Yuan H, Du KJ, He B, Gao SQ, Wen GB, Tan X, Lin YW. Regulation of both the structure and function by a de novo designed disulfide bond: a case study of heme proteins in myoglobin. Chem Commun (Camb). 2018 Apr 24;54(34):4356-4359. doi: 10.1039/c8cc01646a. PMID:29645029 doi:http://dx.doi.org/10.1039/c8cc01646a
