| Structural highlights
Function
WAG31_MYCTU Important for maintaining cell shape and cell wall integrity by localizing peptidoglycan synthesis to the cell poles. Protects PbpB (PBP3, FtsI) from oxidative stress-induced cleavage.[1] [2] [3]
References
- ↑ Kang CM, Nyayapathy S, Lee JY, Suh JW, Husson RN. Wag31, a homologue of the cell division protein DivIVA, regulates growth, morphology and polar cell wall synthesis in mycobacteria. Microbiology (Reading). 2008 Mar;154(Pt 3):725-735. PMID:18310019 doi:10.1099/mic.0.2007/014076-0
- ↑ Mukherjee P, Sureka K, Datta P, Hossain T, Barik S, Das KP, Kundu M, Basu J. Novel role of Wag31 in protection of mycobacteria under oxidative stress. Mol Microbiol. 2009 Jul;73(1):103-19. doi: 10.1111/j.1365-2958.2009.06750.x. Epub, 2009 Jun 1. PMID:19496931 doi:http://dx.doi.org/10.1111/j.1365-2958.2009.06750.x
- ↑ Jani C, Eoh H, Lee JJ, Hamasha K, Sahana MB, Han JS, Nyayapathy S, Lee JY, Suh JW, Lee SH, Rehse SJ, Crick DC, Kang CM. Regulation of polar peptidoglycan biosynthesis by Wag31 phosphorylation in mycobacteria. BMC Microbiol. 2010 Dec 29;10:327. doi: 10.1186/1471-2180-10-327. PMID:21190553 doi:http://dx.doi.org/10.1186/1471-2180-10-327
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