Structural highlights
Function
GFPPS_MYCTU Catalyzes the sequential condensations of isopentenyl pyrophosphate (IPP) with dimethylallyl diphosphate (DMAPP) to yield geranyl diphosphate (GPP) and with GPP to yield (2E,6E)-farnesyl diphosphate (E,E-FPP).[1]
References
- ↑ Abe T, Ozaki S, Ueda D, Sato T. Insight into Isoprenoid Biosynthesis by Functional Analysis of Isoprenyl Diphosphate Synthases from Mycobacterium vanbaalenii and Mycobacterium tuberculosis. Chembiochem. 2020 Oct 15;21(20):2931-2938. PMID:32495977 doi:10.1002/cbic.202000235
