Structural highlights
Function
UBF1_MOUSE Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Pistoni M, Verrecchia A, Doni M, Guccione E, Amati B. Chromatin association and regulation of rDNA transcription by the Ras-family protein RasL11a. EMBO J. 2010 Apr 7;29(7):1215-24. doi: 10.1038/emboj.2010.16. Epub 2010 Feb 18. PMID:20168301 doi:http://dx.doi.org/10.1038/emboj.2010.16
